How to get confidence while powering ON an SMPS prototype?

I never just put power to a first prototype and see what happens. Smoke and loud sounds are the most likely result and then you just know that something was not perfect. So how would you test the next prototype sample?

A good idea is to put supply voltage to your control circuit from an external supply first - often something like 12V. Check oscillator waveform, frequency, gate pulses etc. If possible, use another external power supply to put a voltage to your output. Increasing this voltage slowly, you should see the gate pulses go from max. to min. duty cycle when passing the desired output voltage. If this does not happen, check your feedback path, still without turning main power on.

If everything looks as expected, remove the external supply from the output but keep the control circuit powered from an external source. Then SLOWLY turn up the main input voltage while using your oscilloscope to monitor the voltage waveforms in the power circuit and a DC voltmeter to monitor output voltage etc. Keep an eye on the ampere-meter on the main power source. If something suspicious occurs, stop increasing input further and investigate what's happening while the circuit is still alive.

With a low load you should normally expect the output voltage to hit the desired value soon, at least in a flyback converter. Check that this happens. Then check what happens with a variable load - preferably electronic.

If you did not calculate your feedback loop, very likely you will see self oscillation (normally not destructive). If you don't, use the step load function in your electronic load to check stability. If you see a clear ringing after a load step, you still have some work to do in your loop. But feedback and stability is another huge area which Mr. Ridley has taught us a lot about.

And yes - the world needs powerful POWER ENGINEERS desperately!